As They Made Us is a heartfelt drama film that focuses on the hardships and defining moments of family. It starts with flashbacks of Abigail's life while growing up. Presently, Abigail is a divorced mother of two. Her parents, Barbara and Eugene, need a caregiver because Eugene lost his ability to walk. A doctor says that Eugene only has six months to live. A devastated Abigail visits his estranged brother Nathan to break the news to him. Nathan talks with his father but refuses to see his mother.
Abigail starts to fall in love with a landscaper, Jay. Days before passing away, Eugene declares his love for Barbara. Though Abigail and her mother attend Eugene’s funeral, Nathan is notably absent, claiming he is emotionally unable to. Abigail blames Nathan for not being there during such a difficult time. Six months later the two siblings reconnect when Nathan invites Abigail to a party.