The Ukraine-Russia war has reached a sobering milestone—1,000 days since Russian President Vladimir Putin announced a “special military operation” on February 24, 2022. The conflict, which has claimed thousands of lives, saw an unprecedented escalation as Ukraine launched U.S.-supplied ATACMS missiles, striking Bryansk, a Russian city. While Russian authorities claimed five of the six missiles were intercepted, this marked a pivotal shift in the war’s dynamics. With rising concerns over NATO involvement and Russia’s revised military doctrine permitting nuclear retaliation, fears of a global conflict loom larger than ever. Here’s everything you need to know about this high-stakes development.