Yuri Lowenthal as Davion: a Dragon Knight who hates dragons for massacring his whole family as a boy.
Lara Pulver as Princess Mirana: the exiled princess of the Nightsilver Woods
Tony Todd as Slyrak the Ember Eldwyrm: one of the Eight Great Dragons who is proud and destructive.
Troy Baker as Invoker: a powerful magical Elven Sage who is pivotal to Mirana's quest.
Josh Keaton as Bram: Davion's squire, now serving Kaden in 'curing' Davion of Slyrak's possessing him.
Kari Wahlgren as Luna: once known as Scourge of the Plains, she commits war crimes upon the Elves who refuse to worship Selemene.
Alix Wilton Reganas Selemene: the goddess of the Moon, and an antagonist to the Elven Enclaves who refuse to worship her.
Freya Tingley as Fymryn: a young Elven girl who steals Lotuses from Nightsilver Woods because of a prophecy about her Moon goddess, Mene.
Stephanie Jacobsen as Drysi: leader of the Elven Resistance against the Dark Moon Order's colonization and conversion of her people under Selemene's zealots.
Anson Mount as Kaden: the only Dragon Knight to survive fighting an Eldewyrm.
JB Blanc as Terrorblade: The main antagonist of the series, a demon aiming to kill the dragons in a plan to reshape the universe as he desires.