The only cure for a pandemic that has engulfed the world and brought about the end of humanity is a 14-year-old girl named Ellie. Joel, who is left alone in the world, has the task of delivering Ellie, the cure for the epidemic, to scientists. However, it is uncertain whether Ellie will survive in the hands of scientists searching for a cure. In response, Joel chooses to save Ellie instead of saving humanity. 'The Last of Us' revolves around the story of Ellie, the 14-year-old girl who is the cure for the disease, and Joel, who is left alone.