Set in a fictional country called Daeho, ‘Alchemy of Souls’ is about the love and growth of young magicians as they overcome their twisted fates.
These people's fortunes have been entangled as a result of 'hwanhonsool' (the souls of the dead returning to the living). Jang Wook (Lee Jae-Wook) is a Daeho nobleman from the Jang family. Everyone in the country is aware of a terrible secret about his birth. He is a troublemaker. By chance, Jang Wook meets Mu-Deok (Jung So-Min). Her soul is trapped in a fragile body, yet she is a superb warrior. She takes on the role of Jang Wook's servant while also training him how to fight in secret. Seo Yool (Minhyun) is an aristocratic Seo family descendent. With a good appearance, intelligence, and tremendous martial arts ability, he appears to be perfect. Daeho's crown prince is GoWon (Shin Seung-Ho). He desires to be a monarch who is generous.