The gifted one realizes another fact through time: The things that are making them angry are completely out of their control. These are the consequences of a thing called life. Anger is groundless. This way, the anger transforms into depression.
This way, the questioning mind starts to look for a solution. It looks for a way out of this vicious cycle. Brutal realization of the absurdity of life leads to nihilistic thoughts. Next step is to question the meaning of life and existence. What does life mean, how are we going to embrace the fact that everything is absurd, etc...
These questions can be considered normal during a 'mid-life crisis.' However, if you're constantly questioning your life during your 20's, it indicates a more serious situation. This type of existential depression should be approached carefully, as it might have unpleasant consequences for the individual.